办事指南

Anti-inflammatory drug may be ulcer free

点击量:   时间:2019-03-02 10:16:06

THE first human trials of a non-steroidal anti-inflammatory that is claimed to be as potent as existing drugs but with fewer side effects are set to start within a year. Traditional NSAIDs, such as indomethacin, reduce inflammation by blocking Cox 1 and Cox 2 enzymes. But Cox 1 protects the gut lining, so the drugs can cause ulcers. Adding copper ions to indomethacin prevents the drug interacting with Cox 1 in the gut, says Peter Lay of the University of Sydney,